2026

  1. V.Arvind, E.Nagahara, H.Zhang, P.Shyu, X.Edward Guo, and A. H.Huang, “Comparative Analysis of Tendon Healing in a Clinically Relevant Mouse Model of Achilles Tendon Repair,” Journal of Orthopaedic Research®44 (2026): e70173.

2025

  1. Crosio G, King ER, Huang AH. Regenerative Potential of Neonatal Tendons Is Regulated by Intrinsic Resistance to Inflammation and Supportive T‐Cell–Secreted Factors. The FASEB Journal. 2025;39(20):e71144.

  2. Arvind V, Crosio G, Howell K, Zhang H, Montero A, Huang AH. Functional tendon regeneration is driven by regulatory T cells and IL-33 signaling. Science Advances. 2025;11(17):eadn5409.

  3. Cong T, Li TM, Buller DC, Arvind V, Nasser P, Laudier DM, Ferlauto HR, et al. Tendon Inversion Improves Tendon-to-Bone Healing in a Rat Bicep Tenodesis Model. The Journal of Hand Surgery. 2025.

2024

  1. Kent RN III, Huang AH, Baker BM. Augmentation of tendon and ligament repair with fiber‐reinforced hydrogel composites. Advanced Healthcare Materials. 2024;13(29):2400668.

  2. D'Erminio DN, Adelzadeh KA, Rosenberg AM, Wiener RJ, Torre OM, et al. Regenerative potential of mouse neonatal intervertebral disc depends on collagen crosslink density. iScience. 2024;27(10).

  3. Kent RN III, Jewett ME, Buck TP, Said M, Hold LAA, Crawford EA, et al. Engineered microenvironmental cues from fiber‐reinforced hydrogel composites drive tenogenesis and aligned collagen deposition. Advanced Healthcare Materials. 2024;13(19):2400529.

  4. Arvind V, Shyu PT, Hyman JE, Huang AH. New Insights into Neuromuscular Contracture Reveals Myotendinous-SMAD4 Signaling Underlies Contracture Formation. bioRxiv. 2024:2024.06.11.598573.

  5. Crosio G, King ER, Huang AH. CatWalk XT gait parameters associated with mouse achilles tendon injury and healing. Muscles, Ligaments and Tendons Journal. 2024;14(2):376.

2023

  1. Little D, Amadio PC, Awad HA, Cone SG, Dyment NA, Fisher MB, et al. Preclinical tendon and ligament models: Beyond the 3Rs (replacement, reduction, and refinement) to 5W1H (why, who, what, where, when, how). Journal of Orthopaedic Research. 2023;41(10):2133–2162.

  2. Huang AH, Galloway JL. Current and emerging technologies for defining and validating tendon cell fate. Journal of Orthopaedic Research. 2023;41(10):2082–2092.

2022

  1. Kent RN III, Said M, Busch ME, Poupard ER, Tsai A, Xia J, Matera DL, et al. Physical and soluble cues enhance tendon progenitor cell invasion into injectable synthetic hydrogels. Advanced Functional Materials. 2022;32(48):2207556.

  2. Vervaecke AJ, Carbone AD, Abraham A, Bernstein Z, Laudier D, et al. Tendon progenitor cells as biological augmentation improve functional gait and reduce scar formation after rotator cuff repair. Journal of Shoulder and Elbow Surgery. 2022;31(11):2366–2380.

  3. Walia B, Li TM, Crosio G, Montero AM, Huang AH. Axin2-lineage cells contribute to neonatal tendon regeneration. Connective Tissue Research. 2022;63(5):530–543.

  4. Montero AM, Huang AH. The regenerative capacity of neonatal tissues. Development. 2022;149(12):dev199819.

  5. Crosio G, Huang AH. Innate and adaptive immune cells implicated in tendon healing and disease. European Cells & Materials. 2022;43:39.

2021

  1. Fu C, Huang AH, Galatz LM, Han WM. Cellular and molecular modulation of rotator cuff muscle pathophysiology. Journal of Orthopaedic Research. 2021;39(11):2310–2322.

  2. Moser HL, Abraham AC, Howell K, Laudier D, Zumstein MA, Galatz LM, et al. Cell lineage tracing and functional assessment of supraspinatus tendon healing in an acute repair murine model. Journal of Orthopaedic Research. 2021;39(8):1789–1799.

  3. Arvind V, Huang AH. Reparative and maladaptive inflammation in tendon healing. Frontiers in Bioengineering and Biotechnology. 2021;9:719047.

  4. Kaji DA, Montero AM, Patel R, Huang AH. Transcriptional profiling of mESC-derived tendon and fibrocartilage cell fate switch. Nature Communications. 2021;12(1):4208.

  5. Howell KL, Kaji DA, Li TM, Montero A, Yeoh K, Nasser P, Huang AH. Macrophage depletion impairs neonatal tendon regeneration. FASEB Journal. 2021.

  6. Arvind V, Howell K, Huang AH. Reprogramming adult tendon healing using regenerative neonatal regulatory T cells. bioRxiv. 2021:2021.05.12.443424.

  7. Schlesinger SY, Seo S, Pryce BA, Tufa SF, Keene DR, Huang AH, et al. Loss of Smad4 in the scleraxis cell lineage results in postnatal joint contracture. Developmental Biology. 2021;470:108–120.

  8. Ma C, Jing Y, Li H, Wang K, Wang Z, Xu C, Sun X, Kaji D, Han X, Huang A, et al. ScxLin cells directly form a subset of chondrocytes in temporomandibular joint that are sharply increased in Dmp1-null mice. Bone. 2021;142:115687.

Before 2021

  1. Kreeger PK, Brock A, Gibbs HC, Grande-Allen KJ, Huang AH, Masters KS, et al. Ten simple rules for women principal investigators during a pandemic. PLoS Computational Biology. 2020;16(10):e1008370.

  2. Kaji DA, Howell KL, Balic Z, Hubmacher D, Huang AH. Tgfβ signaling is required for tenocyte recruitment and functional neonatal tendon regeneration. eLife. 2020;9:e51779.

  3. Kaji DA, Tan Z, Johnson GL, Huang W, Vasquez K, Lehoczky JA, Levi B, et al. Cellular plasticity in musculoskeletal development, regeneration, and disease. Journal of Orthopaedic Research. 2020;38(4):708–718.

  4. Torre OM, Mroz V, Benitez ARM, Huang AH, Iatridis JC. Neonatal annulus fibrosus regeneration occurs via recruitment and proliferation of Scleraxis-lineage cells. NPJ Regenerative Medicine. 2019;4(1):23.

  5. Huang AH, Watson SS, Wang L, Baker BM, Akiyama H, Brigande JV, et al. Requirement for scleraxis in the recruitment of mesenchymal progenitors during embryonic tendon elongation. Development. 2019;146(20):dev182782.

  6. Walia B, Huang AH. Tendon stem progenitor cells: Understanding the biology to inform therapeutic strategies for tendon repair. Journal of Orthopaedic Research. 2019;37(6):1270–1280.

  7. Torre OM, Mroz V, Bartelstein MK, Huang AH, Iatridis JC. Annulus fibrosus cell phenotypes in homeostasis and injury: implications for regenerative strategies. Annals of the New York Academy of Sciences. 2019;1442(1):61–78.

  8. Bianco ST, Moser HL, Galatz LM, Huang AH. Biologics and stem cell‐based therapies for rotator cuff repair. Annals of the New York Academy of Sciences. 2019;1442(1):35–47.

  9. Moser HL, Doe AP, Meier K, Garnier S, Laudier D, Akiyama H, et al. Genetic lineage tracing of targeted cell populations during enthesis healing. Journal of Orthopaedic Research. 2018;36(12):3275–3284.

  10. Mohanraj B, Huang AH, Yeger‐McKeever MJ, Schmidt MJ, Dodge GR, et al. Chondrocyte and mesenchymal stem cell derived engineered cartilage exhibits differential sensitivity to pro‐inflammatory cytokines. Journal of Orthopaedic Research. 2018;36(11):2901–2910.

  11. Kim M, Erickson IE, Huang AH, Garrity ST, Mauck RL, Steinberg DR. Donor variation and optimization of human mesenchymal stem cell chondrogenesis in hyaluronic acid. Tissue Engineering Part A. 2018;24(21–22):1693–1703.

  12. Chien C, Pryce B, Tufa SF, Keene DR, Huang AH. Optimizing a 3D model system for molecular manipulation of tenogenesis. Connective Tissue Research. 2018;59(4):295–308.

  13. Torre OM, Das R, Berenblum RE, Huang AH, Iatridis JC. Neonatal mouse intervertebral discs heal with restored function following herniation injury. The FASEB Journal. 2018;32(9):4753.

  14. Arvind V, Huang AH. Mechanobiology of limb musculoskeletal development. Annals of the New York Academy of Sciences. 2017;1409(1):18–32.

  15. Huang AH. Coordinated development of the limb musculoskeletal system: Tendon and muscle patterning and integration with the skeleton. Developmental Biology. 2017;429(2):420–428.

  16. Howell K, Chien C, Bell R, Laudier D, Tufa SF, Keene DR, et al. Novel model of tendon regeneration reveals distinct cell mechanisms underlying regenerative and fibrotic tendon healing. Scientific Reports. 2017;7(1):45238.

  17. Huang AH, Riordan TJ, Pryce B, Weibel JL, Watson SS, Long F, et al. Musculoskeletal integration at the wrist underlies the modular development of limb tendons. Development. 2015;142(14):2431–2441.

  18. Huang AH, Lu HH, Schweitzer R. Molecular regulation of tendon cell fate during development. Journal of Orthopaedic Research. 2015;33(6):800–812.

  19. Farrell MJ, Fisher MB, Huang AH, Shin JI, Farrell KM, Mauck RL. Functional properties of bone marrow-derived MSC-based engineered cartilage are unstable with very long-term in vitro culture. Journal of Biomechanics. 2014;47(9):2173–2182.

  20. Huang AH, Riordan TJ, Wang L, Eyal S, Zelzer E, Brigande JV, et al. Repositioning forelimb superficialis muscles: tendon attachment and muscle activity enable active relocation of functional myofibers. Developmental Cell. 2013;26(5):544–551.

  21. Huang AH, Baker BM, Ateshian GA, Mauck RL. Sliding contact loading enhances the tensile properties of mesenchymal stem cell-seeded hydrogels. European Cells & Materials. 2012;24:29–45.

  22. Huang AH, Hung CT, Mauck RL. Functional cartilage tissue engineering with adult stem cells: Current status and future directions. Stem Cell and Regenerative Medicine. 2012:40–64.

  23. Canuto HC, Fishbein KW, Huang A, Doty SB, Herbert RA, Peckham J, et al. Characterization of skin abnormalities in a mouse model of osteogenesis imperfecta using high resolution magnetic resonance imaging and Fourier transform infrared imaging. NMR in Biomedicine. 2012;25(1):169–176.

  24. Baker BM, Shah RP, Huang AH, Mauck RL. Dynamic tensile loading improves the functional properties of mesenchymal stem cell-laden nanofiber-based fibrocartilage. Tissue Engineering Part A. 2011;17(9–10):1445–1455.

  25. Huang AH, Stein A, Mauck RL. Evaluation of the complex transcriptional topography of mesenchymal stem cell chondrogenesis for cartilage tissue engineering. Tissue Engineering Part A. 2010;16(9):2699–2708.

  26. Nerurkar NL, Sen S, Huang AH, Elliott DM, Mauck RL. Engineered disc-like angle-ply structures for intervertebral disc replacement. Spine. 2010;35(8):867–873.

  27. Bargman R, Huang A, Boskey AL, Raggio C, Pleshko N. RANKL inhibition improves bone properties in a mouse model of osteogenesis imperfecta. Connective Tissue Research. 2010;51(2):123–131.

  28. Huang AH, Farrell MJ, Kim M, Mauck RL. Long-term dynamic loading improves the mechanical properties of chondrogenic mesenchymal stem cell-laden hydrogels. European Cells & Materials. 2010;19:72.

  29. Huang AH, Farrell MJ, Mauck RL. Mechanics and mechanobiology of mesenchymal stem cell-based engineered cartilage. Journal of Biomechanics. 2010;43(1):128–136.

  30. Huang AH. Enhancing mesenchymal stem cell chondrogenesis for cartilage tissue engineering [Dissertation]. University of Pennsylvania; 2010.

  31. Erickson IE, Huang AH, Sengupta S, Kestle S, Burdick JA, Mauck RL. Macromer density influences mesenchymal stem cell chondrogenesis and maturation in photocrosslinked hyaluronic acid hydrogels. Osteoarthritis and Cartilage. 2009;17(12):1639–1648.

  32. Huang AH, Stein A, Tuan RS, Mauck RL. Transient exposure to transforming growth factor beta 3 improves the mechanical properties of mesenchymal stem cell–laden cartilage constructs in a density-dependent manner. Tissue Engineering Part A. 2009;15(11):3461–3472.

  33. Erickson IE, Huang AH, Chung C, Li RT, Burdick JA, Mauck RL. Differential maturation and structure–function relationships in mesenchymal stem cell-and chondrocyte-seeded hydrogels. Tissue Engineering Part A. 2009;15(5):1041–1052.

  34. Huang AH, Motlekar NA, Stein A, Diamond SL, Shore EM, Mauck RL. High-throughput screening for modulators of mesenchymal stem cell chondrogenesis. Annals of Biomedical Engineering. 2008;36(11):1909–1921.

  35. Huang AH, Yeger-McKeever M, Stein A, Mauck RL. Tensile properties of engineered cartilage formed from chondrocyte-and MSC-laden hydrogels. Osteoarthritis and Cartilage. 2008;16(9):1074–1082.

  36. Franco GEL, Huang A, Camacho NP, Stone DS, Blank RD. Increased Young's Modulus and Hardness of Col1a2oim Dentin. Journal of Dental Research. 2006;85(11):1032–1036.

  37. Franco GEL, Huang A, Camacho NP, Blank RD. Dental phenotype of the col1a2oim mutation: DI is present in both homozygotes and heterozygotes. Bone. 2005;36(6):1039–1046